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GLP-1 Medications Now Recommended First for Weight Loss: What Heart Patients Should Know

For years, doctors told patients to try diet and exercise first when trying to lose weight. But that advice is changing. The American College of Cardiology (ACC) now recommends certain medications—called GLP-1 drugs—as a first step in weight management for people at risk of heart disease.

At Cross County Cardiology, we stay up to date with the latest science to help you make informed decisions about your health. This new guidance could mean earlier, more effective support for patients struggling with weight and related heart conditions.

What Are GLP-1 Drugs?

GLP-1 medications like semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound) help with weight loss by mimicking natural hormones in the body. These drugs are given as weekly injections and have been shown to reduce appetite, improve blood sugar, and lower the risk of heart problems in some patients.

What Changed?

The ACC now says that:

✅ Patients don’t need to fail at diet and exercise before starting GLP-1 medications
✅ These drugs can help reduce heart disease risk and are safer than weight loss surgery
✅ Tirzepatide and semaglutide lead to greater weight loss—up to 20% of body weight in some cases

Until now, medications were usually considered a backup option. But new research, like the SELECT and SUMMIT trials, shows that GLP-1 medications help with weight and protect the heart, especially in people with existing cardiovascular disease.

Why This Matters for Heart Health

Obesity plays a big role in heart disease. High blood pressure, cholesterol problems, diabetes, and even heart failure are more likely when someone carries excess weight.

The ACC's guidance recognizes that losing weight through lifestyle alone isn’t always enough—and many people need medical help to lower their cardiovascular risk. These medications may offer that help without the risks of surgery.

Things to Consider

Before starting GLP-1 medications, doctors will look at factors like your Body Mass Index (BMI) and other heart risks. However, these medications can be expensive, with yearly costs over $8,000–$14,000, and are not always covered by insurance.

Some people also experience side effects like:

  • Nausea or upset stomach

  • Eye problems (though rare)

  • Unknown long-term risks for some individuals

What Should You Do?

If you’re concerned about your weight and heart health, talk to your cardiologist about your options. You don’t have to go it alone or wait until things get worse.

At Cross County Cardiology, we offer a personalized approach that combines the latest treatments, expert support, and real solutions to help you live better.

Take the first step—schedule a visit with our team today!

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